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Search Results for " hep g2 "

20

Compounds

Cat No. Product Name Synonyms Targets
T5654 Musk ketone Others
Musk ketone can induce the growth repression and the apoptosis of cancer cells. Musk ketone increases activity of glutathione S-transferase and thus may prove to be useful cancer chemoprotectant.
T1579 Mestranol Devocin,Norquen,Menophase Estrogen Receptor/ERR , Estrogen/progestogen Receptor
Mestranol (Devocin), a semisynthetic estrogen, is used as an estrogen receptor agonist and must be demethylated to be biologically active.
TN2225 Soyasapogenol B Apoptosis , Autophagy
Soyasapogenol B has anti-cancer, hypocholesterolemic, anticomplementary, hepatoprotective effects, it inhibits proliferation of cultured Hep-G2.
TN4562 Oleoside 11-methyl ester Methyloleoside Others
Oleoside 11-methyl ester (Methyloleoside) is a natural product.
T62905 GLS-1-IN-1
GLS-1-IN-1 (compound 1d) is a GLS-1 inhibitor that inhibits Hep G2, MCF 7 and MCF 10A cells.
TN3728 Cudraxanthone L Others
Cudraxanthone L shows the significant hepatoprotective effect on nitrofurantoin-induced cytotoxicity in human liver-derived Hep G2 cells.
T71610 Docosylferulate
Docosylferulate is a biochemical that has been studied for its inhibition on Hep G2 cells and anti-tumor activities.
T13897 Soyasaponin III Others
Soyasaponin III is one of the main potentially bioactive saponins found in soy (Glycine max) and related products,and can induce apoptosis in Hep-G2 cells.
TN5941 2,3-O-Isopropylidenyl euscaphic acid Euscaphic acid acetonide
2,3-O-Isopropylidenyl euscaphic acid shows good hepatoprotective effect,the EC50 value of 88.36±3.25 uM in Hep G2 cells.
T30111 AR 12465 AR-12465
AR 12465 is a trapidil derivative which may affect LDL receptor mediated uptake and degradation of 125 I-LDL by human skin fibroblasts (HSF) and human hepatic cells (HEP G2).
TN4711 Onitin Others
Onitin shows super-oxide and DPPH free radical scavenging effects.It also exhibits hepatoprotective activity on tacrine-induced cytotoxicity in human liver-derived Hep G2 cells.
T73422 CPT-Se4 Topoisomerase
CPT-Se4, a seleno-derivative of Camptothecin (CPT), exhibits enhanced efficacy in cancer cell eradication and tumor suppression. It reduces the GSH/GSSG balance and total thiol content while increasing ROS concentrations...
T81365 Protoapigenone
Protoapigenone, an antineoplastic agent extracted from ferns, demonstrates notable inhibitory activity against various cancer cell lines, including Hep G2, Hep 3B, MCF-7, A549, and MDAMB-231. The respective IC50 values a...
TN4843 Pterisolic acid A Others
Pterisolic acid A shows moderate activity against HCT-116,Hep G2 and BGC-823 cell lines.
TN5961 Gardenolic acid B
Gardenolic acid B shows promising hepatoprotective effects on nitrofurantoin-induced cytotoxicity in human liver-derived Hep G2 cells. Gardenolic acid B shows significant effects on terminating early pregnancy in rats.
T73421 CPT-Se3 Topoisomerase
CPT-Se3, a camptothecin (CPT) seleno-derivative, exhibits enhanced anticancer efficacy by effectively killing cancer cells and hindering tumor proliferation. This compound diminishes the GSH/GSSG ratio and total thiols w...
T78068 O-allylvanillin Others
O-Allylvanillin, an O-allylchalcone derivative, exhibits anti-cancer properties by inhibiting the growth of THP-1, HL60, Hep-G2, and MCF-7 cells with IC50 values of 74.76 μM, 63.52 μM, 90.99 μM, and 90.11 μM, respectivel...
T63304 Topoisomerase II inhibitor 9
Topoisomerase II inhibitor 9 is a Topo II inhibitor (IC50: 0.97 μM) and DNA embedding agent (IC50: 43.51 μM) that blocks the Hep G-2 cell cycle in the G2/M phase and induces apoptosis.
T76527 Hepatitis B Virus Receptor Binding Fragment
Hepatitis B Virus Receptor Binding Fragment (hepatitis B peptide 4980), a synthetic peptide analog, specifically binds to Hep G2 cells and is a potential immunogen anticipated to induce protective antibodies through the ...
TN1464 Camellianin A RAAS
Camellianin A has anticancer activity, it can inhibit the proliferation of the human hepatocellular liver carcinoma Hep G2 and human breast adenocarcinoma MCF-7 cell lines in a dose-dependent manner and induce the signif...
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